Metronidazole 500 mg po bid

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Metronidazole 500 mg is a powerful antibiotic that can help you overcome bacterial infections. With a dosage of 500 mg taken twice daily, you can bid farewell to discomfort and pain caused by infections.

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Main Uses and Benefits

Metronidazole 500 mg is commonly used to treat bacterial infections caused by certain types of microorganisms. It is particularly effective against anaerobic bacteria and some parasites. This medication can be prescribed for various conditions, including:

  • Bacterial infections: Metronidazole is effective in treating infections such as colitis, intra-abdominal infections, and bacterial vaginosis.
  • Protozoal infections: It is also used to treat infections caused by parasites like Giardia and Trichomonas.
  • H. pylori eradication: Metronidazole is part of the treatment regimen for Helicobacter pylori infections in combination with other antibiotics.

Overall, metronidazole is a versatile antibiotic with a broad spectrum of activity, making it a valuable option for many infectious diseases.

Recommended Dosage and Administration

It is essential to follow the prescribed dosage and administration instructions provided by your healthcare provider when taking metronidazole. The recommended dosage for most infections is 500 mg orally twice daily for 7 to 10 days.

For Trichomoniasis:

The typical dosage is 2 grams as a single dose or 500 mg twice daily for 7 days.

If you are unsure about the dosage or have any questions, consult your healthcare provider immediately to avoid any complications or adverse effects.

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Possible Side Effects and Precautions

Metronidazole may cause certain side effects that should be monitored by the prescribing healthcare provider. Common side effects may include:

Side Effect Description
Nausea and vomiting Some patients may experience gastrointestinal upset after taking metronidazole.
Metallic taste A common side effect reported by patients is a metallic or bitter taste in the mouth.
Allergic reactions In rare cases, individuals may develop allergic reactions such as rash, itching, or swelling.

Patients should be advised to notify their healthcare provider if they experience any of the above side effects or if they have any concerns while taking metronidazole. Additionally, it is important to inform the healthcare provider about any allergies or medical conditions before starting metronidazole therapy to prevent adverse reactions.

Drug Interactions and Contraindications

It is important to be aware of potential drug interactions and contraindications when taking Metronidazole. Here are some key points to keep in mind:

Drug Interactions:

Drug Interactions:

  • Metronidazole may interact with alcohol, leading to a disulfiram-like reaction characterized by nausea, vomiting, and flushing. It is important to avoid alcohol while taking this medication.
  • Metronidazole may increase the blood-thinning effects of Warfarin, leading to an increased risk of bleeding. Close monitoring of blood clotting parameters is recommended if these medications are used together.
  • Metronidazole may interact with certain seizure medications, such as Phenytoin or Phenobarbital, leading to decreased effectiveness of both drugs. Dosage adjustments may be necessary if these medications are co-administered.


  • Metronidazole is contraindicated in patients with a history of hypersensitivity to the drug or other nitroimidazole derivatives. Allergic reactions may range from mild rash to severe anaphylaxis.
  • It is contraindicated in the first trimester of pregnancy due to potential teratogenic effects. Consult a healthcare provider before using Metronidazole during pregnancy or while breastfeeding.
  • Patients with a history of certain neurological disorders, such as optic neuritis or peripheral neuropathy, should use Metronidazole with caution due to a risk of exacerbating these conditions.
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Always consult with your healthcare provider or pharmacist before starting Metronidazole to ensure it is safe and appropriate for you, considering your medical history and current medications.

Important Considerations for Patients

Important Considerations for Patients

Patients should follow the prescribed dosage schedule strictly and complete the full course of medication even if symptoms improve.

It is important to avoid alcohol consumption while taking metronidazole as it may cause severe reactions such as nausea, vomiting, and headache.

Pregnancy and Breastfeeding

Metronidazole should be used with caution in pregnant or breastfeeding women. It is essential to consult a healthcare provider before using this medication.

  • Inform your healthcare provider about any existing medical conditions, allergies, or medications you are taking before starting metronidazole treatment.
  • Report any unusual symptoms or side effects to your healthcare provider immediately.